Medroxy - Progesterone
Why has my veterinarian prescribed this medicine?
Medroxy progesterone acetate (MPA) is a hormone. It may be used in cats to treat behavior problems (i.e. roaming, inter male aggressive behavior, spraying, mounting), hair loss and inflammation of the skin. MPA may be used for other conditions as determined by your veterinarian.
How do I give this medication?
- Give this medicine to your pet as directed by your veterinarian. READ THE LABEL CAREFULLY.
- If the medicine is a liquid, measure the dose with reasonable care.
- Try to give this medication at about the same time each day.
- DO NOT give your pet more medicine than directed and DO NOT give the drug more often than directed
- DO NOT stop giving this medication to your pet unless directed by your veterinarian. Call your veterinarian ahead of time if your pet needs a refill.
- Try not to miss giving any doses.
What if I miss giving a dose?
Give the dose as soon as possible. If it is almost time for the next dose, skip the missed dose, and continue with the regular schedule. Do not give the pet two doses at once.
How do I store this medicine?
- Keep this medicine out of reach of children.
- Store this medicine in a cool, dry place at room temperature.
- Do not store this medicine in the bathroom, near the kitchen sink or in damp places. The medicine may break down if exposed to heat or moisture.
What are the potential side effects?
"Notify your veterinarian if any symptoms are troublesome and persist."
- The following side effects have been reported: inflammation of the endometrium (lining of the uterus), excessive thirst, excessive ingestion of food, depression, drowsiness, personality changes, mammary changes, lowered immune response and decrease in sperm production.
- Notify your veterinarian if any symptoms are troublesome and persist.
- Other side effects may occur. If the pet experiences anything unusual, contact your veterinarian.
Are there any possible drug interactions?
- Make sure to tell your veterinarian if you are giving your pet any other medication or supplements.
- Quite often, your veterinarian may prescribe two different medications, and sometimes a drug interaction may be anticipated. If this occurs, your veterinarian may vary the dose and/or monitor your pet more closely.
- No drug interactions have been established. There is a potential MPA may interact with rifampin.
- Contact your veterinarian if your pet experiences any unusual reactions when different medications are given together.
© Copyright 2025 LifeLearn Inc. Used and/or modified with permission under license. This content written by LifeLearn Animal Health (LifeLearn Inc.) is licensed to this practice for the personal use of our clients. Any copying, printing or further distribution is prohibited without the express written consent of LifeLearn. This content does not contain all available information for any referenced medications and has not been reviewed by the FDA Center for Veterinary Medicine, or Health Canada Veterinary Drugs Directorate. This content may help answer commonly asked questions, but is not a substitute for medical advice, or a proper consultation and/or clinical examination of your pet by a veterinarian. Please contact your veterinarian if you have any questions or concerns about your pet’s health. Last updated on Jul 7, 2016.